Enhancing the Toxicity of Cancer Chemotherapeutics with Gold Nanorod Hyperthermia

Tanya S. Hauck, Travis L. Jennings, Tetyana Yatsenko, J. Carl Kumaradas, Warren C. W. Chan

Advanced Materials, Volume 20, Issue 20 | DOI: 10.1002/adma.200800921

Abstract

The heat produced by optically excited gold nanorods is used to augment the chemotherapeutic agent cisplatin in killing tumor cells. This combined therapy kills 78% more cells than cisplatin alone, suggesting a synergistic interaction between these treatments.