Engineering Steps for Mobile Point-of-Care Diagnostic Devices
Ayden Malekjahani, Shrey Sindhwani, Abdullah Muhammad Syed, Warren CW Chan
Acc. Chem. Res. 2019, 52, 9, 2406–2414 | DOI:10.1021/acs.accounts.9b00200
Mobile phone technology is a perfect companion for point-of-care diagnostics as they come equipped with advanced processors, high resolution cameras, and network connectivity. Despite several academic pursuits, only a few mobile phone diagnostics have been tested in the field, commercialized or achieved regulatory approval. This review will address the challenges associated with developing mobile diagnostics and suggest strategies to overcome them. We aim to provide a resource for researchers to accelerate the development of new diagnostics. Our Account includes an overview of published mobile phone diagnostics and highlights lessons learned from their approach to diagnostic development. Also, we have included recommendations from regulatory and public health agencies, such as the U.S. Food and Drug Administration and World Health Organization, to further guide researchers.